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Article title USAGE OF SCANNING PROBE MICROSCOPY FOR INVESTIGATION OF MECHANOACTIVATED BIOLOGICAL MATERIALS PROPERTIES AND THEIR IMPACT ON TISSUE EYE STRUCTURE
Authors O.V. Karban’, Y.G. Vasil’ev, V.V. Zharov, P.A. Perevozhikov, S.I. Leesment, S.V. Timofeev
Section SECTION IV. BIOMEDICAL NANOTECHNOLOGY
Month, Year 04, 2011 @en
Index UDC 576.3.314 579.23.234
DOI
Abstract Changing the fibrous capsula of the eyeball treated by injection of nanosizemechanoactivated biological substance was investigated with usage of Scanning Probe Microscopy (SPM). It was shown that usage of this method together with spectral analysis of cuts provides the way for impartial assessment of main components of cellular and non-cellular biopolymer. The using nanostructured human placenta was showed to accelerate penetration of the graft in recipient sclera and give rise to the forming novel conjunctive tissue. The novel collagen fibrils showed fibrillar properties that were different from those of the mature fibrils. The results obtained show the potentialities of the use of biocontainers with nanostructured human placenta for the treatment of progressive myopia, retina dystrophy, partial optic-nerve atrophy and some other diseases of the eye. The study performed calls for further investigation in this field.

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Keywords CPM; nanostructured biomaterial; eye tissue.
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