Article

Article title THE USE OF DYNAMIC CHARACTERISTICS OF ACOUSTIC WAVES FOR THE PURPOSES OF IMAGING INTERNAL STRUCTURES OF BIOLOGICAL TISSUES
Authors M. V. Laguta, V. V. Grivtsov
Section SECTION I. HYDROACOUSTIC METHODS FOR ECOLOGICAL MONITORING OF THE OCEAN
Month, Year 08, 2017 @en
Index UDC 534.7
DOI 10.23683/2311-3103-2017-8-70-77
Abstract The current state of the environment affects human health, causing the development of diseases of various organ systems, as well as exerting little influence on the human body. Therefore, an urgent task is the development of methods of diseases diagnostics on early stages. The most informative and safe are ultrasonic methods of visualization of human body internal structures. In these methods, the analysis of the dynamics of acoustic wave propagation in biological tissue is usually done on the basis of pressure and particle velocity. However, since the nonlinear interaction of the acoustic wave with the biological tissue is large enough, it also makes a significant contribution to the distortion of the wave profile, allowing you to obtain additional information about the object structure. Therefore, a promising area to date is the development of acoustic tomography based on nonlinear effects. The main objective is to study the relationship between nonlinear parameter and such dynamic characteristics of the acoustic wave as the oscillatory velocity and acceleration to assess the use of vibrational acceleration characteristics of acoustic waves on the basis of which it is possible to obtain the distribution of the nonlinear parameter in the medium. Consideration of the Euler equations of motion in differential form clearly reflects the relationship between local and portable accelerations of the particles of the medium as well as the transition to the particle velocity after simplification of the equation. The calculations of the dynamics of change in particle velocity while passing the acoustic signal through the biological environment with different values of the nonlinearity parameter in the presence of the contribution of the quadratic and cubic nonlinearities. The equation in the second approximation for a harmonic wave has been taken as a basis. All the calculations are performed in Matlab software. To study the dynamics of change of vibrational acceleration in the change of nonlinear parameter equation for particle velocity is differentiated by time. Assessed are the nature and magnitude of the distortion profiles of the vibrational characteristics at different values of the nonlinearity parameter.

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Keywords Acoustic tomography of the nonlinear parameter; harmonics; the biological environment.
References 1. Fizika vizualizatsii izobrazheniy v meditsine [Physics of imaging in medicine]: in 2 vol.
Vol. 2: translation from English, ed. by S. Uebba. Moscow: Izd-vo Mir, 1991, 408 p.
2. Demin I.Yu., Pronchatov-Rubtsov N.V. Sovremennye akusticheskie metody issledovaniy v biologii i meditsine [Modern acoustic methods of research in biology and medicine], Uchebno-metodicheskie materialy po programme povysheniya kvalifikatsii «Khranenie i obrabotka informatsii v biologicheskikh sistemakh» [Training materials for the training program "Storage and processing of information in biological systems"]. Nizhniy Novgorod: Izd-vo NNGU, 2007, 121 p.
3. Fatemi M., Greenleaf J.F. Real-time assessment of the parameter of nonlinearity in tissue using «nonlinear shadowing», Ultrasound in Med. & Biol., 1996, Vol. 22, No. 9, pp. 1215-1228.
4. Kim D.Y., Lee J.S., Kwon S.J., Song T.K. Ultrasound second harmonic imaging with a weighted chirp signal, IEEE Ultrasonics symposium, 2001, pp. 1477-1480.
5. Gemmeke H., Ruiter N.V. 3D ultrasound computer tomography for medical imaging, Science Direct. Nuclear instruments and methods in physics research, 2007, pp. 1057-1065.
6. Zhang D., Chen X., Gong X. Acoustic nonlinearity parameter, tomography for biological tissues via parametric array from a circular piston source. Theoretical analysis and computer simulations, J. Acoust. Soc. Amer., 2001, Vol. 109, No. 3, pp. 1219-1225.
7. Burov V.A., Zotov D.I., Rumyantseva O.D. Vosstanovlenie prostranstvennykh raspredeleniy skorosti zvuka i pogloshcheniya v fantomakh myagkikh biotkaney po eksperimental'nym dannym ul'trazvukovogo tomografirovaniya [The restoration of the spatial distributions of sound velocity and absorption in the phantom of the soft tissues according to the experimental data of ultrasonic tomographybased], Akusticheskiy zhurnal [Akusticheskij Zhurnal], 2015, Vol. 61, No. 2, pp. 254-273.
8. Preobrazhenskiy S.V., Preobrazhenskiy V.L., Perno F., Bu Matar O. Diagnostika ne-odnorodnosti nelineynogo parametra akusticheskoy sredy s pomoshch'yu obrashcheniya vol-novogo fronta ul'trazvuka [Diagnostics of inhomogeneity of the nonlinear acoustic parameter of the medium using phase conjugation of ultrasound], Akusticheskiy zhurnal [Akusticheskij Zhurnal], 2008, Vol. 54, No. 1, pp. 20-25.
9. Burov V.A., Shmelev A.A., Zotov D.I. Prototip tomograficheskoy sistemy, ispol'zuyushchey akusticheskie nelineynye effekty tret'ego poryadka [A prototype of tomographic system using acoustic nonlinear effects of the third order], Akusticheskiy zhurnal [Akusticheskij Zhurnal], 2013, Vol. 59, No. 1, pp. 31-51.
10. Laguta M.V., Chernov N.N., Varenikova A.Yu. K voprosu o postroenii skhem vizualizatsii tomogramm na osnove nelineynoy akustiki [To the question about structuring the visualization of tomograms on the basis of nonlinear acoustics], Sb. trudov XIV Vserossiyskoy nauchno-tekhnicheskoy konferentsii «Meditsinskie informatsionnye sistemy MIS-2016», 19-22 dekabrya 2016, g. Taganrog [Proceedings of the XIV Russian scientific-technical conference "Medical information systems MIS-2016", Taganrog. December 19-22, 2016], pp. 213-225.
11. Laguta M.V., Chernov N.N. K voprosu o bezopasnosti diagnosticheskogo ul'trazvuka dlya introskopii [To the question about the safety of diagnostic ultrasound for imaging], Sb. trudov Nauchno-prakticheskoy konferentsii «Nelineynaya akustika-50» [Proceedings of Scientific-practical conference "Nonlinear acoustics-50"]. Taganrog: Izd-vo YuFU, 2015, pp. 162-166.
12. Varenikova A.Yu. Primenenie dinamicheskoy kharakteristiki nelineynogo vzaimodeystviya akusticheskikh voln dlya vizualizatsii biotkaney [the Use of the dynamic characteristics of nonlinear interaction of acoustic waves for imaging of biological tissues], Sb. materialov Dvadtsat' vtoroy Vserossiyskoy nauchnoy konferentsii studentov fizikov i molodykh uchenykh VNKSF-22 [The collection of proceedings of the Twenty-second national scientific conference of students physicist and young scientists proceedings of RSCSP-22]. Rostov-on-Don: Izd-vo YuFU, 2016, pp. 330-331.
13. Zagray N.P. Nelineynye vzaimodeystviya v sloistykh i neodnorodnykh sredakh: monografiya [The nonlinear interaction in layered and inhomogeneous media: monograph]. Taganrog: Izd-vo TRTU, 1998, 433 p.
14. Lependin L.F. Akustika: ucheb. posobie dlya vuzov [Acoustics: a textbook for universities]. Moscow: Izd-vo Vysshaya shkola. 1978, 488 p.
15. Zarembo L.K., Timoshenko V.I. Nelineynaya akustika [Nonlinear acoustics]. Moscow: Izd-vo MGU, 1984, 104 p.
16. Rudenko O.V., Soluyan S.I. Teoreticheskie osnovy nelineynoy akustiki [Theoretical foundations of nonlinear acoustics]. Moscow: Izd-vo Nauka. 1975, 288 p.
17. Chernov N.N, Mikhralieva A.I, Zagray N.P., Al'-Saman A.Kh. Opredelenie uprugikh svoystv biologicheskikh sloistykh sred na osnove nelineynogo vzaimodeystviya akusticheskikh voln [the Determination of elastic properties of layered biological media based on nonlinear interaction of acoustic waves], Inzhenernyy vestnik Dona [Engineering journal of Don], 2016, № 3. Available at: ivdon.ru/ru/magazine/archive/n3y2016/3735.
18. Laguta M.V., Chernov N.N. Issledovanie vliyaniya nelineynosti biologicheskikh tkaney na protsess prokhozhdeniya ul'trazvukovoy volny [Research of influence of nonlinearity of biologi-cal tissues in the process of passing ultrasonic waves], Sb. trudov XIV Vserossiyskoy nauchno-tekhnicheskoy konferentsii «Meditsinskie informatsionnye sistemy MIS-2016», 19-22 dekabrya 2016, g. Taganrog [Proceedings of the XIV all-Russian scientific-technical conference "Medical information systems MIS-2016". Taganrog. December 19-22, 2016], pp. 187-196.
19. Laguta M.V. Monitoring vzveshennykh i donnykh zagryazneniy pribrezhnykh zon morey [Monitoring of suspended and sediment contamination of coastal zones of seas], Sb. trudov VIII Vserossiyskoy Chernomorskoy shkoly-seminara molodykh uchenykh, aspirantov, studentov i shkol'nikov, may 2017 g., Gelendzhik [Proceedings of the VIII all-Russian the black sea the school-seminar of young scientists, postgraduates, students and pupils. May 2017. Gelendzhik], pp. 171-175.
20. Laguta M.V., Varenikova A.Yu., Chernov N.N. Izmerenie nelineynogo parametra metodom konechnykh amplitud [Measurement of the nonlinearity parameter with finite amplitudes], Sb. trudov V Vserossiyskoy molodezhnoy shkoly-seminara «Innovatsii i perspektivy meditsinskikh informatsionnykh sistem IPMIS-2016», 19–22 dekabrya 2016, g. Taganrog [Proceedings of the V all-Russian youth school-seminar "Innovations and prospects of medical. information systems IPMI-2016". December 19-22, 2016. Taganrog], pp. 80-84.

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